Saffron was detailed in a 7th-century BC Assyrian botanical reference compiled under Ashurbanipal. Documentation of saffron’s use over the span of 4,000 years in the treatment of some 90 illnesses has been uncovered.Saffron-based pigments have indeed been found in 50,000 year-old depictions of prehistoric places in northwest Iran. Ancient Persians cultivated Persian saffron (Crocus sativus ‘Hausknechtii’) in Derbena, Isfahan, and Khorasan by the 10th century BC. At such sites, saffron threads were woven into textiles,ritually offered to divinities, and used in dyes, perfumes, medicines, and body washes.Saffron threads would thus be scattered across beds and mixed into hot teas as a curative for bouts of melancholy.